Four-Drug attack on blood cancer tested for frail patients

NCT ID NCT04009109

Summary

This study is testing a combination of four drugs (lenalidomide, ixazomib, dexamethasone, and daratumumab) for older adults or those too frail for a stem cell transplant who have newly diagnosed multiple myeloma. The goal is to see if adding more drugs during long-term 'maintenance' therapy can better control the cancer and keep it from progressing. Researchers will compare two different maintenance regimens to see which is more effective and tolerable.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Gibbs Cancer Center & Research Institute/Spartanburg Regional Healthcare

    Spartanburg, South Carolina, 29303, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Northern Light Eastern Maine Medical Center

    Bangor, Maine, 04401, United States

  • SUNY Upstate Medical Center

    Syracuse, New York, 13210, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68152, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

Conditions

Explore the condition pages connected to this study.