New drug cocktail shows promise for myeloma patients ineligible for transplant
NCT ID NCT04009109
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a combination of four drugs (lenalidomide, ixazomib, dexamethasone, and daratumumab) in 79 adults newly diagnosed with multiple myeloma who cannot have a stem cell transplant. Participants receive the drugs for 12 cycles, then are split into two groups: one continues with lenalidomide alone, the other with three drugs, both for up to 2 years. The goal is to see which approach better delays the cancer's return or worsening.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Gibbs Cancer Center & Research Institute/Spartanburg Regional Healthcare
Spartanburg, South Carolina, 29303, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Northern Light Eastern Maine Medical Center
Bangor, Maine, 04401, United States
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SUNY Upstate Medical Center
Syracuse, New York, 13210, United States
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University of Nebraska Medical Center
Omaha, Nebraska, 68152, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States