New bacteria slurry takes on poop transplants for stubborn gut infection

NCT ID NCT05911997

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests two treatments for people with repeat C. diff infections: a lab-made bacteria mix called MTC01 and a fecal transplant (FMT) from a healthy donor. Both are given during a colonoscopy. The goal is to see which is safer and better at stopping the infection from coming back. About 60 adults with at least two recent C. diff episodes will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MTC01 (a slurry of bacteria) and fecal microbiota transplantation (FMT) from a healthy donor

What this could lead to

If successful, this could point toward a safer, more effective treatment for recurrent C. difficile infections, reducing the need for repeated antibiotics.

What could go wrong

This is an early Phase 1 trial with only 60 participants, so results may not apply broadly. There are risks of serious side effects, including infection or allergic reactions.

Conditions

The condition(s) this trial relates to.

Clostridium difficile colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.