New hope for MS patients when old treatments fail

NCT ID NCT03933202

Completed Disease control Sponsor: EMD Serono Research & Development Institute, Inc. Source: ClinicalTrials.gov ↗

Summary

This study looked at how well a drug called cladribine tablets worked for people with relapsing multiple sclerosis (MS) when their previous oral or infusion treatments were not controlling their disease well enough. It followed 291 patients in a real-world setting for two years to see if switching to cladribine reduced their MS attacks and improved their quality of life. The main goal was to measure the annual rate of MS relapses, along with patient satisfaction, fatigue, and daily function.

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Contacts and locations

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Locations

Advanced Neurosciences Research, LLC

Fort Collins, Colorado, 80528, United States
Ascension St. Francis Center for Neurological Disorders, S.C.

Milwaukee, Wisconsin, 53215, United States
Associated Neurologists of Southern Connecticut, PC

Fairfield, Connecticut, 06824, United States
Axiom Clinical Research of Florida

Tampa, Florida, 33609, United States
Baptist Health Lexington

Lexington, Kentucky, 40503, United States
Baylor College of Medicine IRB

Houston, Texas, 77030, United States
Blacksburg Neurology, PC

Christiansburg, Virginia, 24073, United States
Central Texas Neurology Consultants

Round Rock, Texas, 78681, United States
College Park Family Care Center

Overland Park, Kansas, 66212, United States
Colorado Springs Neurological Associates, PC - Neurology

Colorado Springs, Colorado, 80907, United States
DENT Neurologic Institute

Amherst, New York, 14226, United States
DHR Health Neurology Institute Neuroimmunology and Multiple Sclerosis

McAllen, Texas, 78503, United States
Dayton Center for Neurological Disorders

Dayton, Ohio, 45459, United States
Detroit Clinical Research Center, PC

Farmington Hills, Michigan, 48334, United States
Fort Wayne Neurological Center

Fort Wayne, Indiana, 46804, United States
Fullerton Neurology and Headache Center

Fullerton, California, 92835, United States
Guilford Neurologic Associates

Greensboro, North Carolina, 27405, United States
HCA Research Institute

Englewood, Colorado, 80113, United States
Insight Neuroscience LLC

Bellevue, Ohio, 44811, United States
Integrated Neurology Services - Dr. Simon Fishman's Office

Alexandria, Virginia, 22310, United States
MS Center of Evergreen

Kirkland, Washington, 98034, United States
Massey Cancer Center - VCU Medical Center

Richmond, Virginia, 23298, United States
Memorial Healthcare

Owosso, Michigan, 48867, United States
Meridian Clinical Research (Neurology)

Norfolk, Virginia, 23502, United States
Minneapolis Clinic of Neurology - Neurology

Golden Valley, Minnesota, 55422, United States
MultiCare Health System Institute for Research and Innovation - MultiCare Health System Institute for Research

Tacoma, Washington, 98405, United States
MultiCare Health System Institute for Research and Innovation - MultiCare Health System Institute for Research and

Spokane, Washington, 99202, United States
Multiple Sclerosis Center of Greater Washington

Vienna, Virginia, 22182, United States
NYU Langone Brooklyn - Brooklyn

Brooklyn, New York, 11220, United States
Neuro Institute of New England P.C.

Foxborough, Massachusetts, 02035, United States
Neurological Associates

Richmond, Virginia, 23226, United States
Neurological Clinical Research Institute

Boston, Massachusetts, 02114, United States
Neurology Associates, P. A.

Maitland, Florida, 32751, United States
Neurology Center of Las Vegas

Las Vegas, Nevada, 89128, United States
Neurology Center of San Antonio

San Antonio, Texas, 78258, United States
Neurology, PC

Knoxville, Tennessee, 37922, United States
Neuroscience Group of Northeast Wisconsin - DUPLICATE

Neenah, Wisconsin, 54956, United States
North Central Neurology Associates, P.C.

Cullman, Alabama, 35058, United States
Northern Light Comprehensive Multiple Sclerosis Care Center

Bangor, Maine, 04401, United States
Northwest Houston Neurology

Cypress, Texas, 77429, United States
Northwest Neurology Ltd

Rolling Meadows, Illinois, 60008, United States
Orlando Health Multiple Sclerosis Comprehensive Care Center - Downtown Orlando

Orlando, Florida, 32806, United States
Prairie Education & Research

Springfield, Illinois, 62702, United States
Premier Neurology Research, P.C.

Greer, South Carolina, 29650, United States
Providence Neurological Specialties

Portland, Oregon, 97225, United States
Raleigh Neurology Associates

Raleigh, North Carolina, 27607-6010, United States
Regina Berkovich MD PhD INC

West Hollywood, California, 90048, United States
Riverhills Neuroscience

Cincinnati, Ohio, 45212, United States
Sentara Ambulatory Care Center

Virginia Beach, Virginia, 23456, United States
Suncoast Neuroscience and Associates, Inc.

St. Petersburg, Florida, 33713, United States
The Boster Center for Multiple Scelosis

Columbus, Ohio, 43235, United States
The Charlotte-Mecklenburg Hospital Authority - Carolinas Healthcare System

Charlotte, North Carolina, 28203, United States
The Elliot Lewis Center for Multiple Sclerosis Care

Wellesley, Massachusetts, 02481, United States
The Medical College of Wisconsin - Endocrinology

Milwaukee, Wisconsin, 53226, United States
The Trustee of Columbia University in the City of New York

New York, New York, 10032, United States
UMASS - Neurology

Worcester, Massachusetts, 01655, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of Miami

Miami, Florida, 33136, United States
University of South Alabama

Mobile, Alabama, 36693, United States
University of South Florida

Tampa, Florida, 33612, United States
University of Toledo - PARENT

Toledo, Ohio, 43614-2598, United States
VCU Medical Center - Pediatric Neurology

Richmond, Virginia, 23298-0211, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Wayne State University (WSU) - Multiple Sclerosis Treatment and Clinical Research Center (MS Center) - Department of Neurology

Detroit, Michigan, 48201, United States
Wills Eye Institute - Ocular Oncology Service - Wills Eye Institute

Philadelphia, Pennsylvania, 19107, United States
Yale University

Fairfield, Connecticut, 06824, United States

Conditions

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MULTIPLE SCLEROSIS