New drug targets Hard-to-Treat cancers with missing gene
NCT ID NCT05245500
First seen Nov 01, 2025 · Last updated Jun 09, 2026 · Updated 28 times
Summary
This early-stage trial tests an experimental drug called MRTX1719 in adults with advanced solid tumors that have a specific missing gene (MTAP deletion). The study includes people with cancers like mesothelioma, lung cancer, and pancreatic cancer that cannot be removed by surgery or have spread. The main goals are to check the drug's safety and see if it can shrink tumors or slow cancer growth.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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Cancer and Hematology Centers of Western Michigan
RECRUITINGNorton Shores, Michigan, 49444, United States
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Dana-Farber Cancer Institute
RECRUITINGBrookline, Massachusetts, 02251, United States
Contact Phone: •••-•••-••••
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David H Koch, Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10021, United States
Contact Phone: •••-•••-••••
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Local Institution - 108
COMPLETEDMilwaukee, Wisconsin, 53226, United States
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Local Institution - 124
WITHDRAWNChicago, Illinois, 60637, United States
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Local Institution - 129
NOT_YET_RECRUITINGMineola, New York, 11501, United States
Contact
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Local Institution - 134
WITHDRAWNSeattle, Washington, 98109, United States
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MDACC
RECRUITINGHouston, Texas, 77030, United States
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Mayo Clinic
RECRUITINGPhoenix, Arizona, 85054-4502, United States
Contact Phone: •••-•••-••••
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Mayo Clinic
RECRUITINGJacksonville, Florida, 32224, United States
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-••••
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New york cancer and blood specialists - Oncology
RECRUITINGPort Jefferson Station, New York, 11776, United States
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New york cancer and blood specialists - Oncology
RECRUITINGPort Jefferson Station, New York, 11776, United States
Contact Phone: •••-•••-••••
Contact
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Rocky Mountain Cancer Centers, LLP - Oncology
RECRUITINGLone Tree, Colorado, 80124, United States
Contact Phone: •••-•••-••••
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Rutgers Cancer Institute of New Jersey
RECRUITINGNew Brunswick, New Jersey, 08901, United States
Contact Phone: •••-•••-••••
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Sarah Cannon Research Institute (SCRI) - HealthONE Location
RECRUITINGDenver, Colorado, 80218-1238, United States
Contact Phone: •••-•••-••••
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Sarah Cannon Research Institute at Florida Cancer Specialists
RECRUITINGOrlando, Florida, 32827, United States
Contact
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South Texas Accelerated Research Therapeutics
RECRUITINGSan Antonio, Texas, 78229, United States
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Texas Oncology - DFW
RECRUITINGFort Worth, Texas, 76104, United States
Contact Phone: •••-•••-••••
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Texas Oncology, P.A. - Oncology
RECRUITINGTyler, Texas, 78503, United States
Contact Phone: •••-•••-••••
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University of North Carolina
RECRUITINGChapel Hill, North Carolina, 27599, United States
Contact
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University of North Carolina - Gastroenterology and Hepatology
RECRUITINGChapel Hill, North Carolina, 27599, United States
Contact
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Ut Southwestern
RECRUITINGDallas, Texas, 75235, United States
Contact
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Vanderbilt - Ingram Cancer Center
RECRUITINGNashville, Tennessee, 37232-5505, United States
Contact Phone: •••-•••-••••
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Virginia Cancer Specialists, PC
RECRUITINGFairfax, Virginia, 22031, United States
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.