New mRNA vaccine tested against deadly brain tumors

NCT ID NCT05938387

Summary

This early-stage study tested a new mRNA vaccine called CVGBM in patients with an aggressive type of brain cancer called glioblastoma. The 37 participants had already undergone surgery and radiation treatment. Researchers gave patients seven vaccine injections over several weeks to check if the treatment was safe and tolerable, while also monitoring for any signs that it might help control the cancer.

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Contacts and locations

Locations

  • CHU de Liège

    Liège, Belgium

  • Erasmusmc Cancer institute

    Rotterdam, South Holland, Netherlands

  • Neurosurgical Clinic at the LMU Munich

    München, Germany

  • Universitair Ziekenhuis Brussel - PPDS

    Brussels, Belgium

  • Universitatsklinikum Leipzig

    Leipzig, Saxony, Germany

  • University Clinic Heidelberg

    Heidelberg, Baden-Wurttemberg, Germany

  • University Clinic Regensburg

    Regensburg, Bavaria, Germany

  • University Hospital Essen

    Essen, North Rhine-Westphalia, Germany

  • Universitätsklinikum Bonn

    Bonn, North Rhine-Westphalia, Germany

  • Universitätsklinikum Frankfurt

    Frankfurt am Main, Hesse, Germany

  • Universitätsklinikum Freiburg

    Freiburg im Breisgau, Baden-Wurttemberg, Germany

  • Universitätsklinikum Tübingen

    Tübingen, Baden-Wurttemberg, Germany

  • Universitätsmedizin Mannheim

    Mannheim, Baden-Wurttemberg, Germany

Conditions

Explore the condition pages connected to this study.