One shot for two viruses? new combo vaccine enters early human testing

NCT ID NCT07464314

Recruiting now ⭐️ VACCINE ⭐️ Sponsor: GlaxoSmithKline Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This early-stage study is testing a new mRNA vaccine that aims to protect against both seasonal flu and COVID-19 with a single shot. Around 1,475 healthy adults aged 65 to 85 will receive either the new combo vaccine, a standard flu vaccine, or a licensed COVID-19 vaccine. Researchers will closely monitor side effects and measure immune responses through blood samples to see how well the body builds defenses against both viruses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mRNA seasonal flu/COVID-19 combination vaccine
What this could lead to: If successful, this could lead to a single annual shot that protects against both flu and COVID-19, simplifying vaccination.
What could go wrong: This is a very early (Phase 1) study focused on safety and immune response, not yet on preventing illness. The vaccine may not work as hoped or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

COVID-19 prevention target influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLUENZA, HUMAN+COVID-19

Contacts and locations

Locations

GSK Investigational Site
RECRUITING

Anniston, Alabama, 36207, United States
GSK Investigational Site
RECRUITING

Little Rock, Arkansas, 72204, United States
GSK Investigational Site
RECRUITING

Fair Oaks, California, 95628, United States
GSK Investigational Site
RECRUITING

San Diego, California, 92123, United States
GSK Investigational Site
RECRUITING

Miami, Florida, 33186, United States
GSK Investigational Site
RECRUITING

Miami Lakes, Florida, 33016, United States
GSK Investigational Site
RECRUITING

West Palm Beach, Florida, 33409, United States
GSK Investigational Site
RECRUITING

Stockbridge, Georgia, 30281, United States
GSK Investigational Site
RECRUITING

Austin, Texas, 78705, United States
GSK Investigational Site
RECRUITING

Charlottesville, Virginia, 22911, United States
GSK Investigational Site
RECRUITING

Newport News, Virginia, 23606, United States
GSK Investigational Site
RECRUITING

Seattle, Washington, 98104, United States