MRNA cancer shots tested in 42 patients with advanced tumors
NCT ID NCT06880549
First seen Feb 05, 2026 · Last updated May 30, 2026 · Updated 18 times
Summary
This early-stage study tests two experimental mRNA treatments (mRNA-4106 and mRNA-4200) in 42 people with advanced solid tumors that have not responded to standard therapy. The goal is to check safety and tolerability, with mRNA-4200 given alongside a checkpoint inhibitor. This is a dose-escalation study, meaning the dose increases gradually to find the safest level.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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START Midwest
Grand Rapids, Michigan, 49546, United States
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START Mountain Region
West Valley City, Utah, 84119, United States
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START San Antonio
San Antonio, Texas, 78229, United States
Conditions
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