Smart blood tests may personalize lung cancer care after targeted therapy

NCT ID NCT04841811

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether using a sensitive blood test (MRD) to guide follow-up treatment can improve outcomes for people with a specific type of advanced lung cancer (EGFR-mutant stage III NSCLC). Participants first receive a targeted pill (aumolertinib), then a team of doctors decides on local therapy (surgery or radiation). After that, the blood test helps decide if maintenance therapy should continue. The goal is to see if this personalized approach works better and is safe. About 192 adults aged 18-70 with good performance status are being studied.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Guangdong Lung cancer institute

    Guangzhou, Guangdong, 510080, China

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