New study could spare liver donors from unnecessary needle biopsies

NCT ID NCT07015723

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Erasmus Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a special MRI scan (MRCP) can accurately measure liver fat in people who want to donate part of their liver. Currently, donors need a liver biopsy, which is invasive and carries risks. The researchers will compare MRCP results with biopsy results from 90 donors to see if the scan is reliable enough to replace the biopsy. If successful, it could make donor screening faster, safer, and less uncomfortable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If MRCP proves as accurate as biopsy, future living liver donors could avoid an invasive procedure, making the screening process quicker and safer.
What could go wrong: This is an observational study, not a treatment trial. MRCP may not reliably detect all levels of liver fat, so biopsy might still be needed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVING DONOR LIVER TRANSPLANTATION

Contacts and locations

Locations

Erasmus Medical Center

Rotterdam, South Holland, 3015 GD, Netherlands

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