MRI-Guided radiation may shrink inoperable colon tumors
NCT ID NCT06244537
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This early-phase trial is testing whether a precise MRI-guided radiation technique (MR-Linac) can help shrink advanced colon cancers that cannot be surgically removed. Twenty participants will receive short-course radiation followed by chemotherapy, then surgery if possible. The goal is to see if this approach is safe and can make surgery an option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- MR-Linac radiotherapy and chemotherapy (mFOLFOX6 or XELOX)
- What this could lead to
- If successful, this approach could make surgery possible for some patients with colon cancer that was previously considered inoperable.
- What could go wrong
- This is a very early, small phase I trial with only 20 participants. The combination of radiation and chemotherapy may cause significant side effects, and it is unknown if it will improve long-term outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SAFETY AND EFFICACY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sichuan Cancer Hospital & Institute, Affiliated Cancer Hospital of University of Electronic Science and Technology of China.
RECRUITINGChengdu, Sichuan, 610042, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.