Can freezing tumors control prostate cancer recurrence?

NCT ID NCT01727284

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether MR-guided cryoablation—a procedure that freezes tumors—can effectively treat prostate cancer that has come back in the prostate bed. Researchers are enrolling 107 patients whose tumors are small and not suitable for surgery or radiation. The goal is to see if the frozen tumors are controlled over three years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MR-guided cryoablation (a procedure that uses extreme cold to freeze and destroy tumor tissue, guided by MRI)

What this could lead to

If successful, this could offer a non-surgical option to control prostate cancer recurrences in the prostate bed, potentially delaying or avoiding more aggressive treatments.

What could go wrong

This is a single-arm study without a comparison group, so it's unclear if cryoablation is better than other options. The procedure may not fully eliminate the tumor, and there are risks like damage to nearby structures (rectum, urethra).

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States