Could a simple ultrasound replace MRI for spotting dangerous prostate cancer?

This study compares two imaging methods—multiparametric ultrasound (mpUS) and multiparametric MRI (mpMRI)—to see which better detects clinically significant prostate cancer in men scheduled for their first biopsy. Participants receive both scans before biopsy, and if either shows a suspicious area, targeted biopsies are taken alongside standard systematic samples. The goal is to determine whether the less expensive and more widely available ultrasound can match MRI's accuracy in finding aggressive cancers.