Could a simple mouthwash soothe chronic mouth pain?
NCT ID NCT07280442
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a mouthwash containing sodium hyaluronate and Sh-Oligopeptide-85 can reduce pain and sores in people with oral lichen planus, a chronic inflammatory condition. Forty adults with painful mouth lesions will use either the test mouthwash or a standard corticosteroid mouthwash for four weeks. Researchers will measure changes in pain and lesion severity to see if the new option works as well as steroids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sodium hyaluronate 0.01% and Sh-Oligopeptide-85 SP mouthwash
What this could lead to
If it works, this mouthwash could offer a gentler option to reduce pain and sores from oral lichen planus without using steroids.
What could go wrong
This is a small, early-phase trial with only 40 people, so results may not apply to everyone. The mouthwash may not improve symptoms, and individual responses vary.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Departamento de Especialidades Clínicas Odonotlógicas, Facultad de Odontología, Universidad Complutense de Madrid
Madrid, 28040, Spain
Contact