Can a gentler mouthwash win kids over without sacrificing gum health?
NCT ID NCT07662226
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a hyaluronic acid mouthwash is more acceptable to children than a standard chlorhexidine mouthwash, while still controlling plaque-induced gingivitis. Thirty-two children aged 8 to 12 with signs of gingivitis will use one of the two mouthwashes. Researchers will measure taste acceptance using a faces scale and track gum health with standard dental indices. The goal is to find a mouthwash that children will actually use, improving their oral hygiene habits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hyaluronic acid mouthwash (Q-Afta®) and chlorhexidine 0.12% mouthwash (Hexitol®)
- What this could lead to
- If hyaluronic acid mouthwash tastes better and works as well as chlorhexidine, it could improve children's willingness to use mouthwash regularly, helping control gingivitis.
- What could go wrong
- This is a small, early-phase trial with only 32 children, so results may not apply to all kids. Hyaluronic acid may not be as effective as chlorhexidine at reducing plaque or gum inflammation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of dentistry, Cairo university
Cairo, Egypt, 11411, Egypt
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Other studies related to the condition(s) this trial covers.