Knee replacement patients may get better pain relief with morphine in the bone
NCT ID NCT06716749
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 16 times
Summary
This study tested whether adding morphine (a painkiller) to a standard antibiotic injection into the shin bone during knee replacement surgery helps reduce pain afterward. About 100 adults having their first knee replacement took part. Half got the antibiotic plus morphine, and half got the antibiotic alone. Researchers measured pain scores and how much extra pain medication patients needed after surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Carilion Clinic
Roanoke, Virginia, 24014, United States
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