New hope for rare VEXAS syndrome: drug trial targets inflammation

NCT ID NCT07098936

First seen Jan 07, 2026 · Last updated May 14, 2026 · Updated 22 times

Summary

This study tests a drug called momelotinib in 57 adults with VEXAS syndrome, a rare inflammatory disease that often requires high-dose steroids. The goal is to see if momelotinib can control symptoms and allow lower steroid doses. Participants will take the drug daily, and doctors will check their response over 24 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Lyon sud - Service d'Hématologie Clinique

    RECRUITING

    Pierre-Bénite, 69495, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU Estaing - Service d'Hématologie Clinique

    NOT_YET_RECRUITING

    Clermont-Ferrand, 63000, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU Nantes - Hôtel Dieu - Service d'Hématologie Clinique

    NOT_YET_RECRUITING

    Nantes, 44093, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU d'Angers - Service des Maladies du sang

    NOT_YET_RECRUITING

    Angers, 49933, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Haut-Lévèque - Centre F. Magendie - Service des Maladies du sang

    NOT_YET_RECRUITING

    Pessac, 33604, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Tours - Hôpital Bretonneau - Service de Médecine Interne

    NOT_YET_RECRUITING

    Tours, 37044, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Claude Huriez - Service de Médecine Interne

    NOT_YET_RECRUITING

    Lille, 59037, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Pontchaillou Service d'hématologie clinique et service de médecine interne

    NOT_YET_RECRUITING

    Rennes, 35033, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Saint Louis - Service hématologie séniors

    NOT_YET_RECRUITING

    Paris, 75010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Saint-Antoine - Service de Médecine Interne

    NOT_YET_RECRUITING

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • IUCT Oncopole Département d'hématologie / Unité de médecine interne

    NOT_YET_RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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