Scientists dive into DNA of rare lymphoma to predict outcomes

NCT ID NCT05700149

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at tumor samples from 300 people with nodal marginal zone lymphoma, a rare blood cancer. Researchers want to find genetic patterns that help predict how the disease will behave. The goal is to better understand the disease and improve future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to more personalized treatment strategies for nodal marginal zone lymphoma.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly benefit participants. Results may not change clinical practice immediately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Lymphoma, B-Cell, Marginal Zone nodal marginal zone B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AO SS Antonio e Biagio e C. Arrigo

    RECRUITING

    Alessandria, AL, 15121, Italy

  • AOU Maggiore della Carità

    RECRUITING

    Novara, 28100, Italy

  • AOU Policlinico Vittorio Emanuele, Presidio Ferrarotto

    RECRUITING

    Catania, CT, 95123, Italy

  • ASST Grande Ospedale Metropolitano Niguarda

    RECRUITING

    Milan, MI, 20162, Italy

  • ASST Papa Giovanni XXIII

    RECRUITING

    Bergamo, BG, 24127, Italy

  • ASST degli Spedali Civili di Brescia

    RECRUITING

    Brescia, BS, 25123, Italy

  • ASST dei Sette Laghi - Ospedale di Circolo di Varese

    RECRUITING

    Varese, VA, 21100, Italy

  • AUSL IRCCS di Reggio Emilia, Arcispedale S. Maria Nuova

    RECRUITING

    Reggio Emilia, RE, 42123, Italy

  • Azienda Ospedaliera Papardo

    RECRUITING

    Messina, ME, 98158, Italy

  • Azienda Ospedaliera Universitaria Careggi

    RECRUITING

    Florence, FI, 50134, Italy

  • Azienda Ospedaliera Universitaria Federico II

    RECRUITING

    Naples, 80131, Italy

  • Azienda Ospedaliero Universitaria di Ferrara

    RECRUITING

    Cona, FE, 44124, Italy

  • Azienda Sanitaria Locale di Pescara

    RECRUITING

    Pescara, PE, 65124, Italy

  • CHU Grenoble Alpes

    RECRUITING

    Grenoble, 38043, France

  • Centro di Riferimento Oncologico

    RECRUITING

    Aviano, PN, 33081, Italy

  • Chonnam National University Hwasun Hospital

    RECRUITING

    Jeollanam-do, 58128, South Korea

  • Clatterbridge Cancer Centre Liverpool

    RECRUITING

    Liverpool, L7 8YA, United Kingdom

  • Fondazione IRCCS Policlinico San Matteo

    RECRUITING

    Pavia, PV, 27100, Italy

  • Fondazione PTV - Policlinico Tor Vergata

    RECRUITING

    Rome, RM, 00133, Italy

  • Fondazione Policlinico Univeristario A. Gemelli, IRCCS, Università Cattolica S. Cuore

    RECRUITING

    Rome, RM, 00168, Italy

  • Hematology Center after Prof. Yeolyan

    RECRUITING

    Yerevan, Armenia

  • Hospital Clinic I Provincial de Barcelona

    RECRUITING

    Barcelona, 08036, Spain

  • Hospital Italiano de Buenos Aires

    RECRUITING

    Buenos Aires, C1199ABB, Argentina

  • Hospital Universitari de Bellvitge / Institut Català d'Oncologia

    RECRUITING

    L'Hospitalet de Llobregat, 08907, Spain

  • Hospital del Mar

    RECRUITING

    Barcelona, 08003, Spain

  • Hôpitaux Universitaires Genevois

    RECRUITING

    Geneva, Switzerland

  • IEO Istituto Europeo di Oncologia

    RECRUITING

    Milan, MI, 20141, Italy

  • IRCCS - Azienda Ospedaliero-Universitaria di Bologna

    RECRUITING

    Bologna, 40138, Italy

  • IRCCS Ospedale San Raffaele

    RECRUITING

    Milan, MI, 20132, Italy

  • Institut Universitaire du Cancer de Toulouse

    RECRUITING

    Toulouse, 31059, France

  • Istituto Tumori "Giovanni Paolo II" I.R.C.C.S.

    RECRUITING

    Bari, BA, 70124, Italy

  • Kantonsspital St. Gallen

    RECRUITING

    Sankt Gallen, 9007, Switzerland

  • Leicester Royal Infirmary

    RECRUITING

    Leicester, LE1 5WW, United Kingdom

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Norfolk and Norwich University Hospital

    RECRUITING

    Norwich, NR4 7UY, United Kingdom

  • Ohio Health Riverside Methodist Hospital

    RECRUITING

    Columbus, Ohio, 43214, United States

  • Oncology Institute of Southern Switzerland and Institute of Oncology Research

    RECRUITING

    Bellinzona, 6500, Switzerland

  • Oxford University Hospitals

    RECRUITING

    Oxford, OX3 7LE, United Kingdom

  • Portuguese Institute of Oncology

    RECRUITING

    Lisbon, 1099-023, Portugal

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Canada

  • Rijnstate Hospital

    RECRUITING

    Arnhem, Netherlands

  • Royal Bournemouth Hospital

    RECRUITING

    Bournemouth, BH7 7DW, United Kingdom

  • Sapienza University - AOU Policlinico Umberto I

    RECRUITING

    Rome, RM, 00161, Italy

  • Tata Memorial Hospital

    RECRUITING

    Mumbai, India

  • University Clinical Center, Medical University of Gdansk

    RECRUITING

    Gdansk, 80-211, Poland

  • University Hospital Basel

    RECRUITING

    Basel, Switzerland

  • University Hospital Centre Zagreb

    RECRUITING

    Zagreb, 10000, Croatia

  • University Hospital Zurich

    RECRUITING

    Zurich, 8091, Switzerland

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

  • Weill Cornell Medical

    RECRUITING

    New York, New York, 10065, United States

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