Gene hunt for rare muscle diseases could unlock future treatments

NCT ID NCT00272883

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This research study at Boston Children's Hospital is looking at the genes and proteins involved in congenital myopathies—rare muscle diseases that are present from birth. Researchers will analyze DNA from up to 4,000 participants, including patients and their family members, to find new disease-causing genes. The goal is to improve diagnosis and, eventually, develop better treatments for these conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could lead to better genetic tests and pave the way for future treatments for congenital myopathies.

What could go wrong

This is an observational study, not a treatment trial. It may take many years before findings translate into therapies, and not all genetic discoveries will lead to effective treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

central core myopathy centronuclear myopathy congenital fiber-type disproportion myopathy congenital myopathy congenital structural myopathy Minicore Myopathy with External Ophthalmoplegia multiminicore myopathy nemaline myopathy rigid spine muscular dystrophy 1 RYR1-related myopathy SELENON-related myopathy Thomsen and Becker disease X-linked myotubular myopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Genetics Division, Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••