Ancient herb mix put to the test against stubborn hives

NCT ID NCT04967092

Completed Disease control Sponsor: Prof. Lin Zhixiu Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether a modified version of the traditional Chinese herbal formula Xiao-Feng Powder can reduce itching and wheals in people with chronic urticaria (hives lasting more than 6 weeks). About 58 adults will receive either the herbal granules or a placebo twice daily for 12 weeks, along with the antihistamine bilastine. The study measures changes in a daily hive-and-itch score to see if adding the herbal formula improves symptom control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a modified Chinese herbal formula called Xiao-Feng Powder, taken as granules twice daily for 12 weeks, plus the antihistamine bilastine
What this could lead to: If effective, this herbal formula could offer a new option for managing chronic hives with fewer side effects than standard treatments.
What could go wrong: This is a small, early-phase trial, so results may not apply broadly. Herbal products can vary in quality and may cause allergic reactions or interact with other medications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic urticaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC URTICARIA

Contacts and locations

Locations

The Chinese University of Hong Kong

Shatin, Hong Kong

More trials for these conditions

Other studies related to the condition(s) this trial covers.