Could a histamine shot tame chronic hives?

NCT ID NCT07680413

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study looks at how well an injection called Immunoglobulin-Histamine complex (IHC, brand name Histoglob) works for people with chronic urticaria, or long-term hives. Researchers will track 600 patients in India to see if the treatment reduces hives and the need for other allergy medications. The goal is to understand its real-world effectiveness and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Immunoglobulin-Histamine complex (IHC) injection
What this could lead to
If effective, this could offer a new option for managing chronic urticaria, potentially reducing reliance on antihistamines and improving quality of life.
What could go wrong
This is an observational study, not a controlled trial, so results may be less conclusive. The treatment may not work for everyone, and allergic reactions are possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aakash Healthcare Super Speciality Hospital

    RECRUITING

    New Delhi, National Capital Territory of Delhi, 110075, India

  • Aarvya Hospital

    RECRUITING

    Gurgaon, Haryana, 122505, India

  • Anand Multispeciality Hospital

    RECRUITING

    Pune, Maharashtra, 411039, India

  • Apex Hospital Pvt. Ltd.

    RECRUITING

    Jaipur, Rajasthan, 302017, India

  • Ayushri Multispeciality Hospital.

    RECRUITING

    Pune, Maharashtra, 411017, India

  • Chandni Hospital Private Limited

    RECRUITING

    Kanpur, National Capital Territory of Delhi, 208002, India

  • Christian Medical Collage & Hospital

    RECRUITING

    Ludhiana, Punjab, 141008, India

  • D. Y. Patil Medical College and Research Centre

    RECRUITING

    Navi Mumbai, Maharashtra, 400706, India

  • DRG Skin Clinic

    RECRUITING

    Faridabad, Haryana, 121010, India

  • Department of Skin & V.D S.P Medical Collage & A.G of Hospital

    RECRUITING

    Kolkata, West Bengal, 700014, India

  • Dr Astha Sharma Clinic

    RECRUITING

    New Delhi, National Capital Territory of Delhi, 110058, India

  • Dr Utsa Basu Clinic

    RECRUITING

    Kolkata, West Bengal, 700014, India

    Contact Email: •••••@•••••

  • Dr Vaibhav Skin , Hair and Laser Clinic

    RECRUITING

    New Delhi, National Capital Territory of Delhi, 110058, India

  • Ishwar Institute of Healthcare

    RECRUITING

    Aurangabad, Maharashtra, 431002, India

  • Jawahar Lal Nehru hospital

    RECRUITING

    Ajmer, Rajasthan, 305001, India

  • Jupiter Hospital and Research Centre

    RECRUITING

    Vadodara, Gujarat, 390012, India

  • KIMS hospital

    RECRUITING

    Bangalore, Karnataka, 560004, India

  • KPL Hospital

    RECRUITING

    Kolkata, West Bengal, 700084, India

  • KR hospital

    RECRUITING

    Mysore, Karnataka, 570001, India

  • L. G. Hospital

    RECRUITING

    Ahmedabad, Gujarat, 380008, India

  • Lifepoint Multispeciality Hospital

    RECRUITING

    Pune, Maharashtra, 411057, India

  • Mahatma Gandhi Hospital

    RECRUITING

    Jaipur, Rajasthan, 302022, India

  • Matis Multispeciality Hospital

    RECRUITING

    Ahmedabad, Gujarat, 380005, India

  • Medipoint Hospital

    RECRUITING

    Pune, Maharashtra, India

  • Mediskin Hospital

    RECRUITING

    Pune, Maharashtra, 413102, India

  • Medstar Speciality Hospital

    RECRUITING

    Bangalore, Karnataka, 560092, India

  • Mittal Skin Hair Laser and Cosmetic

    RECRUITING

    Jaipur, Rajasthan, 302039, India

  • NRS Medical College and Hospital

    RECRUITING

    Kolkata, West Bengal, 700014, India

  • Parikh Multispeciality Hospital

    RECRUITING

    Vadodara, Gujarat, 390020, India

  • Renukai Critical Care and Multispeciality Hospital

    RECRUITING

    Nanded, Maharashtra, 431602, India

  • SMS Medical Collage and Hospital

    RECRUITING

    Jaipur, Rajasthan, 302004, India

  • Sai Allergy Asthma Eye Hospital

    RECRUITING

    Pune, Maharashtra, 411009, India

  • Saikrupa Hospital

    RECRUITING

    Pune, Maharashtra, 411033, India

    Contact Email: •••••@•••••

  • Silver Streak Multispeciality Hospital

    RECRUITING

    Gurgaon, Haryana, 122004, India

  • Skin & Hair Clinic (Aesthetic Clinic)

    RECRUITING

    New Delhi, National Capital Territory of Delhi, 110058, India

  • SkinXperts Super Speciality Skin, Hair and Laser Clinic

    RECRUITING

    Bangalore, Karnataka, 560086, India

  • Upasana Diagnostic Centre

    RECRUITING

    Kolkata, West Bengal, 700064, India

  • Vaidya Skin Care Clinic

    RECRUITING

    Pune, Maharashtra, 411030, India

  • Vaishnavis skin Care & Cosmetic

    RECRUITING

    Ahmedabad, Gujarat, 380004, India

  • Venkateshwar Hospital

    RECRUITING

    New Delhi, National Capital Territory of Delhi, 110075, India

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