Engineered immune cells take on Hard-to-Treat ovarian cancer

NCT ID NCT03017131

First seen Apr 11, 2026 · Last updated May 15, 2026 · Updated 6 times

Summary

This early-stage trial tests a new treatment for ovarian, fallopian tube, or peritoneal cancer that has returned or not responded to standard therapy. Patients receive their own immune cells (T cells) that have been genetically modified to recognize and attack cancer cells, along with a drug called decitabine that may make the cancer cells easier to target. The main goal is to check the safety of this combination in a small group of 9 participants.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

Conditions

Explore the condition pages connected to this study.