Bacteria vs. cancer: modified salmonella starves tumors in new trial

NCT ID NCT05103345

First seen May 05, 2026 · Last updated May 09, 2026 · Updated 1 time

Summary

This study tests a modified Salmonella bacteria (SGN1) injected directly into tumors to see if it is safe and can shrink advanced solid tumors that have not responded to other treatments. The bacteria are designed to grow inside tumors and cut off their food supply (methionine), starving the cancer cells. About 70 adults with advanced solid tumors will take part. The goal is to find the best dose and check for side effects and tumor response.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • China Medical University Hospital

    RECRUITING

    Taichung, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangdong Clifford Hospital

    RECRUITING

    Guangzhou, Guangdong, 511495, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Taipei Medical University-Shuang Ho Hospital,Ministry of Health and Welfare

    RECRUITING

    New Taipei City, 23561, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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