Bacteria battle cancer: modified salmonella starves tumors in new trial

NCT ID NCT05103345

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a modified salmonella bacteria (SGN1) injected directly into tumors. The bacteria are designed to grow inside tumors and cut off their food supply (an amino acid called methionine), causing the tumors to shrink. The trial involves about 70 adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and find the best dose, while also seeing if the treatment can control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • China Medical University Hospital

    RECRUITING

    Taichung, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangdong Clifford Hospital

    RECRUITING

    Guangzhou, Guangdong, 511495, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Taipei Medical University-Shuang Ho Hospital,Ministry of Health and Welfare

    RECRUITING

    New Taipei City, 23561, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••