New Mini-Open spine surgery aims to cut recovery time for spinal stenosis patients

NCT ID NCT07279051

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a modified mini-open spine surgery (mMO-TLIF) works as well as or better than traditional open surgery for people with lumbar spinal stenosis and instability. About 224 adults aged 18 to 80 with persistent leg pain or walking problems will be randomly assigned to one of the two surgeries. Researchers will track pain, disability, blood loss, hospital stay, and complications over two years to see which approach offers better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

modified mini-open transforaminal lumbar interbody fusion (mMO-TLIF) surgery

What this could lead to

If successful, this modified surgery could offer patients with lumbar spinal stenosis a less invasive option that reduces blood loss, shortens hospital stays, and speeds up recovery while still effectively relieving pain and improving function.

What could go wrong

This is a single-center trial with 224 participants, so results may not apply to all patients. The modified surgery is still a major spine procedure with risks like infection or nerve injury, and it may not prove superior to the standard open approach.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lumbar spinal stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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