Doctor-Tailored stent graft aims to tame deadly aortic aneurysms

NCT ID NCT02989948

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study tests a stent graft that doctors modify to fit each patient's unique aneurysm in the chest and abdomen. The goal is to see if this less invasive approach is as safe and effective as traditional open surgery. About 80 people aged 50 and older with large aneurysms will take part. Success is measured by survival, complications, and whether the aneurysm is sealed off at one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
physician-modified aortic stent graft
What this could lead to
If successful, this could offer a less invasive treatment option for complex aortic aneurysms, potentially reducing recovery time and complications compared to open surgery.
What could go wrong
This is a single-arm study with only 80 participants, so results may not apply to all patients. The graft is modified by the physician, which could lead to variability in outcomes, and there are risks like rupture or device failure.

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Conditions

The condition(s) this trial relates to.

aortic aneurysm Aortic Aneurysm, Thoracoabdominal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dartmouth-Hitchcock Medical Center

    ACTIVE_NOT_RECRUITING

    Lebanon, New Hampshire, 03766, United States

  • Yale New Haven Hospital

    RECRUITING

    New Haven, Connecticut, 06510, United States

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