New drug tested for Tough-to-Treat blood cancer

NCT ID NCT03215030

Terminated Disease control Sponsor: Teva Branded Pharmaceutical Products R&D LLC Source: ClinicalTrials.gov ↗

Summary

This study tested a new drug called modakafusp alfa for people with multiple myeloma, a type of blood cancer, that had returned or stopped responding to at least three prior treatments. The main goals were to find a safe and effective dose and to see if the drug could help control the cancer. The drug was given by IV infusion, and the study was divided into parts to first test safety and then measure how well the drug worked.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AON SS Antonio e Biagio e Cesare Arrigo

Alessandria, 15121, Italy
Ad-Vance Medical Research

Ponce, PR, 00730, Puerto Rico
Alexandra General Hospital of Athens

Athens, Attica, 11528, Greece
Ankara Universitesi

Yenimahalle, Ankara, 06560, Turkey (Türkiye)
Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele

Catania, 95125, Italy
Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona

Ancona, 60126, Italy
Azienda Ospedaliero-Universitaria di Bologna - Policlinico Sant'Orsola-Malpighi

Bologna, 40138, Italy
Baptist Cancer Center - Memphis - Walnut Grove

Memphis, Tennessee, 38120, United States
Boston Medical Center

Boston, Massachusetts, 02118, United States
British Columbia Cancer Agency Vancouver Centre

Vancouver, British Columbia, V5Z 4E6, Canada
Centre Hospitalier Regional Universitaire de Lille

Lille, Hauts-de-France, 59037, France
Centre Hospitalier Universitaire Henri Mondor

Créteil, Île-de-France Region, 91010, France
Centre Hospitalier Universitaire Nantes - Hotel Dieu

Nantes, Pays de la Loire Region, 44093, France
Centre Hospitalier Universitaire de Poitiers

Poitiers, Poitou-charentes, 86000, France
Centre Hospitalier Universitaire de Toulouse Hopital Purpan

Toulouse, Midi-pyrenees, 31059, France
Centre Hospitalier d'Argenteuil - Centre Hospitalier Victor Dupouy

Argenteuil, 95107, France
Centre de Recherche du CHUM

Montreal, Quebec, H2X 0C1, Canada
Chonnam National University Hwasun Hospital

Hwasun, Jeollanam-do, 58128, South Korea
Dana Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Evaggelismos General Hospital

Athens, Attica, 10676, Greece
Fondazione IRCCS Policlinico San Matteo

Pavia, 27100, Italy
Gabrail Cancer Center

Canton, Ohio, 44718-2566, United States
Genesis Care - Milton Keynes

Milton Keynes, England, MK14 6LS, United Kingdom
Genesis Care Windsor - Genesis Care UK Ltd.

Windsor, England, SL43HD, United Kingdom
Hadassah Medical Center

Jerusalem, 9112001, Israel
Henan Cancer Hospital

Zhengzhou, Henan, 450003, China
Highlands Oncology Group

Springdale, Arkansas, 72762, United States
Hopital Necker-Enfants Malades

Paris, Île-de-France Region, 75015, France
Hopital Saint-Antoine

Paris, Île-de-France Region, 75012, France
Hopital Saint-Vincent de Paul - Lille

Lille, Hauts-de-France, 59020, France
Hospital Clinic de Barcelona

Barcelona, 08036, Spain
Hospital Espanol Auxilio Mutuo

San Juan, 00919, Puerto Rico
Hospital Universitari Germans Trias i Pujol

Badalona, Barcelona, 08916, Spain
Hospital Universitari Vall d'Hebron

Barcelona, 08035, Spain
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Hospital Universitario Marques de Valdecilla

Santander, 39008, Spain
Hospital Universitario Virgen de la Arrixaca

Murcia, 30120, Spain
Hospital Universitario de Salamanca

Salamanca, 37007, Spain
Institut de cancerologie Strasbourg Europe

Strasbourg, Alsace, 67200, France
Investigative Clinical Research of Indiana, LLC

Noblesville, Indiana, 46062, United States
Japanese Red Cross Medical Center

Tokyo, 150-8935, Japan
John Theurer Cancer Center

Hackensack, New Jersey, 07601, United States
Johns Hopkins Hospital

Baltimore, Maryland, 21287, United States
June E. Nylen Cancer Center

Sioux City, Iowa, 51101, United States
Juravinski Cancer Centre

Hamilton, Ontario, L8V 5C2, Canada
Levine Cancer Center

Charlotte, North Carolina, 28402, United States
Levine Cancer Institute - Concord

Concord, North Carolina, 28205, United States
Los Angeles Cancer Network - Glendale Adventist Medical Center

Glendale, California, 91204, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
Lumi Research

Houston, Texas, 77002, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
Nagoya City University Hospital

Nagoya, Aichi-ken, 467-8601, Japan
Nanjing Drum Tower Hospital

Nanjing, Jiangsu, 210008, China
National Hospital Organization Okayama Medical Center

Okayama, Okayama-ken, 701-1192, Japan
National Taiwan University Hospital

Taipei, 100, Taiwan
Northwestern Medicine - Northwestern Medical Group

Chicago, Illinois, 60611, United States
Office of James R. Berenson MD

West Hollywood, California, 90069, United States
Ogaki Municipal Hospital

Gifu, Gifu, 503-8502, Japan
Ondokuz Mayis Universitesi Tp Fakultesi

Samsun, 55139, Turkey (Türkiye)
Oregon Health and Science University

Portland, Oregon, 97239, United States
Oslo Universitetssykehus-Ulleval Hospital

Oslo, 0450, Norway
Oxford University Hospitals NHS Foundation Trust

Oxford, England, OX3 7LE, United Kingdom
Peking University People's Hospital

Beijing, Beijing Municipality, 100044, China
Peking University Third Hospital

Beijing, Beijing Municipality, 100089, China
Royal Cornwall Hospital NHS Trust

Cornwell, England, TR1 3LI, United Kingdom
Seoul National University Hospital

Seoul, 03080, South Korea
Shanghai Fourth People's Hospital

Shanghai, Shanghai Municipality, 200003, China
Sir Mortimer B. Davis Jewish General Hospital

Montreal, Quebec, H3T 1E2, Canada
Smilow Cancer Hospital at Yale New Haven

New Haven, Connecticut, 06520, United States
Sun Yat-Sen University Cancer Center

Guangzhou, Guangdong, 510060, China
Tel Aviv Sourasky Medical Center

Tel Aviv, 6423906, Israel
The Catholic University of Korea - Seoul St. Mary's Hospital

Seoul, 06591, South Korea
The Chaim Sheba Medical Center

Ramat Gan, Tel Aviv, 52621, Israel
The First Affiliated Hospital of Soochow University - Suzhou First People's Hospital

Suzhou, Jiangsu, 215006, China
The First Affiliated Hospital, Zhejiang University

Hangzhou, Zhejiang, 310003, China
The Ohio State University

Columbus, Ohio, 43210, United States
The Royal Marsden NHS Foundation Trust

Sutton, England, SM2 5PT, United Kingdom
Tianjin Medical University Cancer Institute & Hospital

Tianjin, Tianjin Municipality, 300060, China
Tri-Service General Hospital

Taipei, Taipei CITY, 11490, Taiwan
USOR - Comprehensive Cancer Centers of Nevada - Central Valley

Las Vegas, Nevada, 89119, United States
Univeristy of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
Universitatsklinik Tubingen

Tübingen, Baden-Wurttemberg, 72076, Germany
Universitatsklinikum Leipzig

Leipzig, Saxony, 04103, Germany
University College London Hospitals NHS Foundation Trust

London, England, NW1 2BU, United Kingdom
University Hospital Kyoto Prefectural University of Medicine

Kyoto, Kyoto, 602-855, Japan
University Hospitals Birmingham NHS Foundation Trust

Birmingham, England, B9 5SS, United Kingdom
University Regional General Hospital of Patras

Patra, Peloponnese, 26504, Greece
University of California Irvine

Orange, California, 92868, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
University of Rochester

Rochester, New York, 14627, United States
Winship Cancer Institute of Emory University

Atlanta, Georgia, 30322, United States
Wuhan Union Hospital

Wuhan, Hubei, 430023, China
Zhongnan Hospital of Wuhan University

Wuhan, Hubei, 430071, China

Conditions

Explore the condition pages connected to this study.

MULTIPLE MYELOMA