App aims to keep teen heart transplant patients alive and healthy

NCT ID NCT05732779

Recruiting now Disease control Sponsor: University of Florida Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study tests a mobile app that lets teen heart transplant patients record themselves taking their anti-rejection medication. The goal is to improve medication adherence and reduce the risk of organ rejection and hospital stays. About 100 teens aged 10-21 who have had a heart transplant will use the app, and researchers will track their medication levels, rejection episodes, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mobile health app for video directly observed therapy
What this could lead to: If it works, this could provide a practical tool to help teen heart transplant patients stick to their medication schedule, potentially reducing rejection episodes and hospitalizations.
What could go wrong: This is a relatively small trial (100 participants) testing a behavioral intervention, not a new drug. Success depends on teens actually using the app consistently, and results may not apply to all transplant patients.

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Conditions

The condition(s) this trial relates to.

Health Behavior Medication Adherence Patient Participation transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTH BEHAVIOR HEART TRANSPLANT REJECTION IMMUNE SUPPRESSION MEDICATION NONADHERENCE PATIENT ENGAGEMENT PEDIATRIC HEART TRANSPLANT REMOTE MONITORING

Contacts and locations

Locations

FSU College of Medicine
NOT_YET_RECRUITING

Tallahassee, Florida, 32306, United States
Joe DiMaggio Children's Hospital
RECRUITING

Hollywood, Florida, 33021, United States
University of Florida
RECRUITING

Gainesville, Florida, 32610, United States
University of Miami, Miller School of Medicine
RECRUITING

Coral Gables, Florida, 33146, United States

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