Can a tiny artery block stop brain bleeds from coming back?

NCT ID NCT07751887

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This trial is testing whether a minimally invasive procedure called middle meningeal artery embolization (MMAE), when combined with standard surgery, can prevent chronic subdural hematoma from recurring. Chronic subdural hematoma is a collection of blood on the brain's surface that can cause pressure and symptoms. The study will include 200 adults with this condition, and they will receive MMAE either before or after surgical drainage. The main goal is to see if this combination reduces the need for repeat surgery within 90 days, while also monitoring for complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Middle meningeal artery embolization (a minimally invasive procedure that blocks blood flow to the membrane around the hematoma)
What this could lead to
If effective, this combined approach could reduce the need for repeat surgeries and improve recovery for people with chronic subdural hematoma.
What could go wrong
The procedure carries risks like stroke or bleeding, and it's unclear if it will significantly lower recurrence rates compared to surgery alone.

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Conditions

The condition(s) this trial relates to.

Hematoma, Subdural, Chronic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Hradec Kralove

    Hradec Králové, 500 05, Czechia

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