Liver function and drug dosing: a closer look at ulonivirine
NCT ID NCT05093972
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This study investigates how a single dose of the drug ulonivirine is processed by the body in people with mild or moderate liver impairment compared to healthy volunteers. Researchers measure drug levels in the blood over time to see if liver function affects how the drug is broken down and cleared. The goal is to understand whether dose adjustments may be needed for people with liver problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a single 400 mg oral dose of ulonivirine (MK-8507)
- What this could lead to
- If successful, this study could help doctors determine the right dose of ulonivirine for people with liver problems.
- What could go wrong
- This is a small, early-phase study focused on drug levels, not on treating a disease. Results may not apply to people with more severe liver impairment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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