New hope for Hard-to-Treat prostate cancer: early trial shows promise

NCT ID NCT06104449

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This early-stage study tested a new drug called opevesostat (MK-5684) in 7 Japanese men with a type of advanced prostate cancer that no longer responds to standard hormone therapy. The main goals were to check the drug's safety and how the body processes it. All participants had already tried other treatments, including chemotherapy.

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Contacts and locations

Locations

  • National Cancer Center Hospital East ( Site 0001)

    Kashiwa, Chiba, 277-8577, Japan

  • Toho University Sakura Medical Center ( Site 0003)

    Sakura, Chiba, 285-8741, Japan

  • Yokohama City University Medical Center ( Site 0002)

    Yokohama, Kanagawa, 232-0024, Japan

Conditions

Explore the condition pages connected to this study.