New combo therapy shows promise in fight against advanced colon cancer
NCT ID NCT05600309
First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 24 times
Summary
This study tested a new drug combination (MK-4280A) in Chinese adults with advanced colorectal cancer that had spread and was no longer responding to standard treatments. The goal was to see if the new combo helps people live longer compared to usual care. About 94 participants took part in this phase 3 trial.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Affiliated Hospital of Jiangnan University(Wuxi Fourth People's Hospital ) ( Site 1185)
Wuxi, Jiangsu, 214122, China
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Changzhou Cancer Hospital-Department of Oncology ( Site 1183)
Changzhou, Jiangsu, 213000, China
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Chongqing Cancer Hospital ( Site 1151)
Chongqing, Chongqing Municipality, 400030, China
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Fudan University Shanghai Cancer Center ( Site 1176)
Shanghai, Shanghai Municipality, 201321, China
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Fujian Province Cancer Hospital ( Site 1178)
Fuzhou, Fujian, 350014, China
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Guangxi Medical University Affiliated Tumor Hospital ( Site 1158)
Nanning, Guangxi, 531021, China
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Hainan General Hospital ( Site 1177)
Haikou, Hainan, 570311, China
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Hubei Cancer Hospital ( Site 1152)
Wuhan, Hubei, 430079, China
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Hunan Cancer Hospital ( Site 1174)
Changsha, Hunan, 410013, China
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Jilin Cancer Hospital ( Site 1163)
Changchun, Jilin, 130012, China
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Jinan Central Hospital ( Site 1167)
Jinan, Shandong, 250000, China
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Shanghai Tenth People's Hospital ( Site 1170)
Shanghai, Shanghai Municipality, 200072, China
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Sir Run Run Shaw Hospital-Medical Oncology ( Site 1173)
Hangzhou, Zhejiang, 310018, China
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Southern Medical University Nanfang Hospital ( Site 1154)
Guangzhou, Guangdong, 510515, China
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Sun Yat-Sen University Cancer Center ( Site 1150)
Guangzhou, Guangdong, 510060, China
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The Second Affiliated Hospital of Anhui Medical University ( Site 1179)
Hefei, Anhui, 230601, China
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The Sixth Affiliated Hospital of Sun Yat-sen University ( Site 1159)
Guangzhou, Guangdong, 510655, China
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The Third Xiangya Hospital of Central South University ( Site 1175)
Changsha, Hunan, 410013, China
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Tianjin Medical University Cancer Institute and Hospital ( Site 1161)
Tianjin, Tianjin Municipality, 300060, China
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West China Hospital Sichuan University ( Site 1172)
Chengdu, Sichuan, 332001, China
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Wuhan Union Hospital Cancer Center ( Site 1162)
Wuhan, Hubei, 430022, China
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Xiangya Hospital Central South University ( Site 1171)
Changsha, Hunan, 410008, China
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Yunnan Province Cancer Hospital-Colorectal surgery ( Site 1169)
Kunming, Yunnan, 650106, China
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Zhejiang Cancer Hospital ( Site 1180)
Hangzhou, Zhejiang, 310005, China
Conditions
Explore the condition pages connected to this study.