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New drug combo targets tough cancers in early trial

NCT ID NCT06049212

Ongoing Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a new drug called MK-2870, either alone or with the immunotherapy pembrolizumab, in Japanese patients with advanced solid tumors or a type of lung cancer. The main goal is to check the safety and side effects of these treatments. About 30 people will take part to find the best dose and see how the body handles the drugs.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autosomal dominant Parkinson disease 4 neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL-CELL LUNG CANCER PROGRAMMED CELL DEATH 1 LIGAND 1(PDL1, PD-L1) PROGRAMMED CELL DEATH 1 LIGAND 2 (PDL2, PD-L2) PROGRAMMED CELL DEATH-1 (PD1, PD-1) SOLID TUMORS

Contacts and locations

Locations

  • Aichi Cancer Center ( Site 0006)

    Nagoya, Aichi-ken, 464-8681, Japan

  • Kanagawa Cancer Center ( Site 0004)

    Yokohama, Kanagawa, 241-8515, Japan

  • Kansai Medical University Hospital ( Site 0007)

    Hirakata, Osaka, 573-1191, Japan

  • National Cancer Center Hospital ( Site 0001)

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East ( Site 0002)

    Kashiwa, Chiba, 277-8577, Japan

  • National Hospital Organization Shikoku Cancer Center ( Site 0008)

    Matsuyama, Ehime, 791-0280, Japan

  • Shizuoka Cancer Center ( Site 0005)

    Nagaizumi-cho,Sunto-gun, Shizuoka, 411-8777, Japan