New hope for tough blood cancer: experimental drug MK-1045 enters key trials
NCT ID NCT05579132
First seen Sep 30, 2025 · Last updated May 09, 2026 · Updated 21 times
Summary
This study tests a new drug called MK-1045 for people with a type of blood cancer (precursor B-cell acute lymphoblastic leukemia) that has returned or no longer responds to standard treatments. The study has two parts: first, finding a safe and tolerable dose, and second, checking how well that dose works. About 203 adults and children aged 2 and older will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hematology Hospital of Chinese Academy of Medical Sciences ( Site 0001)
RECRUITINGTianjin, Tianjin Municipality, 301617, China
Contact Phone: •••-•••-••••
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Henan Cancer Hospital-hematology department ( Site 0002)
RECRUITINGZhengzhou, Henan, 450008, China
Contact Phone: •••-•••-••••
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Southern Medical University Nanfang Hospital ( Site 0004)
RECRUITINGGuangzhou, Guangdong, 510515, China
Contact Phone: •••-•••-••••
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The Affiliated Hospital of Xuzhou Medical University ( Site 0007)
ACTIVE_NOT_RECRUITINGXuzhou, Jiangsu, 221006, China
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The Children's Hospital of Zhejiang University School of Medicine ( Site 0009)
COMPLETEDHangzhou, Zhejiang, 310003, China
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The First Hospital of Harbin ( Site 0005)
RECRUITINGHarbin, Heilongjiang, 150010, China
Contact Phone: •••-•••-••••
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The Second Affiliated Hospital of Third Military Medical University ( Site 0008)
RECRUITINGChongqing, Chongqing Municipality, 400037, China
Contact Phone: •••-•••-••••
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The Second Hospital of Hebei Medical University ( Site 0003)
RECRUITINGShijiazhuang, Hebei, 050000, China
Contact Phone: •••-•••-••••
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Tongji Hospital affiliated to Tongji Medical College of HUST ( Site 0006)
RECRUITINGWuhan, Hubei, 430030, China
Contact Phone: •••-•••-••••
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Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology ( Site 0010)
RECRUITINGWuhan, Hubei, 430022, China
Contact Phone: •••-•••-••••
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West China Second University Hospital, Sichuan University ( Site 0011)
COMPLETEDChengdu, Sichuan, 610000, China
Conditions
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