New drug shows promise for stubborn genetic cholesterol
NCT ID NCT05952869
Summary
This study tested whether an experimental drug called MK-0616 could lower 'bad' cholesterol (LDL-C) better than a placebo in adults with a genetic form of high cholesterol. Over 300 participants who were already on standard cholesterol medication received either the drug or a dummy injection for 24 weeks. The main goal was to see how much LDL-C was reduced and to check the drug's safety.
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Contacts and locations
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Locations
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Advanced Pharma Research ( Site 0007)
Cutler Bay, Florida, 33189, United States
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Alliance for Multispecialty Research, LLC ( Site 0023)
Daphne, Alabama, 36526, United States
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Amsterdam UMC, locatie AMC-Vascular Medicine Clin Trial Unit ( Site 1954)
Amsterdam, North Holland, 1105 AZ, Netherlands
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Arcturus Healthcare , PLC, Troy Internal Medicine Research Division ( Site 0001)
Troy, Michigan, 48098, United States
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CDIEM ( Site 0814)
Providencia, Region M. de Santiago, 7500859, Chile
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Changi General Hospital ( Site 3211)
Singapore, Central Singapore, 529889, Singapore
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Ciensalud Ips S A S ( Site 0903)
Barranquilla, Atlántico, 08001, Colombia
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Clalit Health Services - Sakhnin Community Clinic-Research Unit ( Site 1700)
Sakhnin, 308100, Israel
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Clinica de la Costa S.A.S. ( Site 0902)
Barranquilla, Atlántico, 080020, Colombia
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Clinical Research Chile SpA ( Site 0804)
Valdivia, Los Ríos Region, 5110683, Chile
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Clinical Site Partners LLC, dba CSP Orlando ( Site 0028)
Winter Park, Florida, 32789, United States
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Debreceni Egyetem Klinikai Kozpont-Belgyógyászati Klinika (Anyagcsere Tanszék) ( Site 1601)
Debrecen, 4032, Hungary
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Diex Recherche Trois-Rivieres ( Site 0513)
Trois-Rivières, Quebec, G9A 4P3, Canada
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Ecogene-21 ( Site 0510)
Chicoutimi, Quebec, G7H 7K9, Canada
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Enroll SpA ( Site 0803)
Santiago, Region M. de Santiago, 7500587, Chile
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Excel Medical Clinical Trials ( Site 0008)
Boca Raton, Florida, 33434, United States
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Fakultni Nemocnice u sv. Anny v Brne ( Site 3604)
Brno, South Moravian, 60200, Czechia
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Fakultní nemocnice Brno Bohunice-Interni kardiologicka klinika ( Site 3602)
Brno, Brno-mesto, 625 00, Czechia
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Franciscan Physician Network - Indiana Heart Physicians ( Site 0040)
Indianapolis, Indiana, 46237, United States
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Fundación Centro de Investigación Clínica CIC ( Site 0906)
Medellín, Antioquia, 050021, Colombia
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HOSPITAL CLINICO DE VALENCIA ( Site 2321)
Valencia, Valenciana, Comunitat, 46010, Spain
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Hadassah Medical Center ( Site 1709)
Jerusalem, 9112001, Israel
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Health Research of Hampton Roads, Inc. ( Site 0020)
Newport News, Virginia, 23606, United States
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Hospital de Sant Joan Despí Moisès Broggi ( Site 2335)
Sant Joan Despí, Catalonia, 08970, Spain
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Incor - Instituto do Coracao ( Site 0703)
São Paulo, 05403-000, Brazil
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Institut Klinicke a Experimentalni Mediciny ( Site 3601)
Prague, Praha 4, 140 21, Czechia
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Institut de Cardiologie de Montreal ( Site 0506)
Montreal, Quebec, H1T 1C8, Canada
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Instituto Dante Pazzanese de Cardiology-Fundação Adib Jatene ( Site 0701)
São Paulo, São Paulo, 04012-909, Brazil
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Jubilee Clinical Research ( Site 0030)
Las Vegas, Nevada, 89106, United States
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Mackay Memorial Hospital -Tamshui Branch ( Site 3109)
New Taipei City, New Taipei, 251, Taiwan
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Meilahden tornisairaala - Meilahti Tower Hospital ( Site 1300)
Helsinki, Uusimaa, 00290, Finland
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National Cheng Kung University Hospital-Internal Medicine ( Site 3107)
Tainan, 704, Taiwan
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National Taiwan University Hospital ( Site 3100)
Taipei, 10002, Taiwan
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National University Hospital-Department of Medicine ( Site 3212)
Singapore, Central Singapore, 119074, Singapore
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New Zealand Clinical Research (Christchurch) ( Site 2901)
Christchurch, Canterbury, 8011, New Zealand
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Nordlandssykehuset ( Site 2001)
Bodø, Nordland, 8005, Norway
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Oslo Universitetssykehus Aker-Lipidklinikken ( Site 2000)
Oslo, 0316, Norway
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Pacific Clinical Research Network - Rotorua ( Site 2902)
Rotorua, Bay of Plenty, 3010, New Zealand
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Pontificia Universidad Catolica de Chile-CICUC ( Site 0812)
Santiago, Region M. de Santiago, 8330034, Chile
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Prince of Wales Hospital ( Site 3304)
Shatin, NT, Hong Kong
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Progressive Medical Research ( Site 0021)
Port Orange, Florida, 32127, United States
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Queen Mary Hospital-Medical ( Site 3300)
Pok Fu Lam, Hong Kong
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Rabin Medical Center ( Site 1717)
Petah Tikva, 4941492, Israel
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Radboudumc-internal medicine ( Site 1952)
Nijmegen, Gelderland, 6525 GA, Netherlands
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Royal Prince Alfred Hospital-6West CV Ambulatory Care ( Site 2808)
Camperdown, New South Wales, 2050, Australia
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SALUT SANT JOAN DE REUS-BAIX CAMP (EDP)-Vascular and Metabolism Unit ( Site 2329)
Reus, Tarragona, 43204, Spain
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Salud SURA Calle 100 ( Site 0918)
Bogotá, Cundinamarca, 110231, Colombia
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Semmelweis Egyetem-Városmajori Szív- és Érgyógyászati Klinika ( Site 1600)
Budapest, 1122, Hungary
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Shaare Zedek Medical Center ( Site 1710)
Jerusalem, 9103102, Israel
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Shin Kong Wu Ho-Su Memorial Hospital ( Site 3106)
Taipei City, Taipei, 111, Taiwan
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Synexus Clinical Research US - Evansville ( Site 0031)
Evansville, Indiana, 47714, United States
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Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Belgyógyászati Klinika ( Site 1603)
Szeged, Csongrád megye, 6725, Hungary
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Universidade Federal Do Ceara ( Site 0702)
Fortaleza, Ceará, 60430-270, Brazil
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Universitair Medisch Centrum Utrecht-Vascular Medicine Research ( Site 1955)
Utrecht, 3584 CX, Netherlands
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Vasculair Onderzoek Centrum Hoorn ( Site 1953)
Hoorn, North Holland, 1625 HV, Netherlands
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Velocity Clinical Research at The Pioneer Heart Institute, Lincoln ( Site 0026)
Lincoln, Nebraska, 68506, United States
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Velocity Clinical Research, Salt Lake City ( Site 0004)
West Jordan, Utah, 84088, United States
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Victorian Heart Hospital-Monash Cardiovascular Research Centre (MCRC) ( Site 2803)
Clayton, Victoria, 3168, Australia
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Wake Forest Baptist Health-Cardiovascular Medicine ( Site 0041)
Winston-Salem, North Carolina, 27157, United States
Conditions
Explore the condition pages connected to this study.