Could fixing immune cell batteries help fight sepsis?
NCT ID NCT04439617
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study checked whether the energy-producing parts (mitochondria) of certain immune cells work differently in ICU patients with severe infections (sepsis) compared to those without infection. Researchers used leftover blood from routine tests to measure these changes in 36 patients. The goal is to better understand why immune cells sometimes go into a dormant state, which can make infections worse, and to find new ways to treat sepsis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could point toward new treatments that restore immune cell energy to fight severe infections.
- What could go wrong
- This is a small, observational study that only checks for changes in cell function. It does not test any treatment, so it may not lead to a therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chu Dijon Bourgogne
Dijon, 21000, France
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Other studies related to the condition(s) this trial covers.
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