Scientists observe mitochondrial mutation carriers to unlock disease secrets
NCT ID NCT01532791
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 300 people who carry a specific mitochondrial DNA mutation (m.3243A>G) that can cause symptoms like migraines, seizures, and hearing loss. Researchers will use brain scans, muscle tests, and cognitive assessments to track how the disease progresses over time. No treatment is given; the goal is to gather information that may help develop future therapies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better understand mitochondrial diseases and pave the way for future treatments.
- What could go wrong
- This is an observational study with no treatment, so it will not directly improve symptoms. It may take years to yield useful results.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Columbia University
RECRUITINGNew York, New York, 10032, United States