Can mirikizumab mend the gut? new trial aims for deep healing in Crohn's
NCT ID NCT07292012
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if the drug mirikizumab can heal damage deep in the gut wall in people with Crohn's disease. About 75 adults with active symptoms and inflammation seen on MRI will receive the drug. The main goal is to see if the gut shows at least 25% improvement after 24 weeks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CH de Valence
NOT_YET_RECRUITINGValence, 26000, France
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CHU de Brest - Hôpital de la Cavale Blanche
NOT_YET_RECRUITINGBrest, 29200, France
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CHU de Clermont Ferrand - Hôpital d'Estaing
RECRUITINGClermont-Ferrand, 63003, France
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CHU de Nîmes Carémeau
NOT_YET_RECRUITINGNîmes, 30029, France
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CHU de Toulouse - Hôpital Rangueil
NOT_YET_RECRUITINGToulouse, 31059, France
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Institut Mutualiste Monsouris
NOT_YET_RECRUITINGParis, 75674, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Which diet do IBD patients prefer? intermittent fasting, mediterranean, or low FODMAP?
- Can better detection of precancerous lesions in IBD prevent colorectal cancer?
- Which biologic best stops Crohn's from coming back after surgery?
- New biologic mirikizumab put to the test against standard therapies for IBD
- Blood and stool tests could revolutionize IBD monitoring