2000-Patient study aims to predict heart risks from leaky valve

NCT ID NCT06876883

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

The MIRACLE study is following 2000 adults diagnosed with moderate or severe mitral regurgitation, a common heart valve problem. Researchers will use detailed heart ultrasound exams and track patients over time to identify factors that raise the risk of death or heart failure hospitalization. The goal is to build a clinical model that helps doctors make better treatment decisions for this condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could lead to a better way to predict which patients with mitral regurgitation are at highest risk, helping doctors decide who needs early treatment.
What could go wrong
This is an observational study, not a treatment trial. It will not test any new drug or procedure, so it cannot directly improve outcomes. The model may not be accurate for all patient groups.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of Sun Yat-sen Univerity

    RECRUITING

    Guangzhou, Guangdong, 510000, China

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