Can targeted therapy ease the mental health toll of stigma in LGBTQ+ people?

NCT ID NCT06614868

Recruiting now Symptom relief Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a type of counseling called Acceptance and Commitment Therapy (ACT) can reduce minority stress—the internalized stigma from social marginalization—in LGBTQ+ individuals. Researchers will compare ACT to standard counseling in 80 non-heterosexual adults. The goal is to see if reducing minority stress leads to lower depression, anxiety, and PTSD, and improved well-being.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Acceptance and Commitment Therapy (counseling)
What this could lead to: If effective, this counseling approach could offer a tailored way to reduce depression, anxiety, and PTSD in LGBTQ+ people by addressing the root cause of minority stress.
What could go wrong: This is a small early-stage study with 80 participants, so results may not apply to everyone. The therapy is unstructured, making it hard to know which parts work best.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MINORITY STRESS

Contacts and locations

Locations

University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294, United States

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