Mindfulness may boost opioid treatment success
NCT ID NCT05042388
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding mindfulness-based relapse prevention (MBRP) to standard care helps people with opioid use disorder stay on their medication (extended-release naltrexone) and avoid drug use after leaving a residential treatment program. About 105 participants were randomly assigned to either MBRP or usual treatment and followed for three months after discharge. The goal was to see if MBRP improves medication adherence and reduces opioid relapse and craving.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Mindfulness-Based Relapse Prevention (MBRP) behavioral therapy
What this could lead to
If it works, this could offer a practical way to help people with opioid use disorder stay on their medication and reduce the chance of relapse after leaving residential treatment.
What could go wrong
This is a small, completed study (105 participants) testing a behavioral program, not a new drug. Results may not apply to everyone, and the benefits may be modest or hard to maintain long-term.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Gaudenzia, Inc. (West Chester House)
West Chester, Pennsylvania, 19382, United States