Can a sugar mimic fix cystic fibrosis?

NCT ID NCT02325362

First seen Nov 20, 2025 · Last updated Apr 28, 2026 · Updated 17 times

Summary

This study tested a drug called miglustat in 16 adults with cystic fibrosis who have a specific genetic mutation (F508del). The goal was to see if miglustat could help restore the function of a faulty protein that controls salt and water movement in the lungs. Researchers measured changes in nasal electrical activity as a sign of improvement. The study was small and early-stage, so more research is needed to know if it truly helps patients.

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Contacts and locations

Locations

  • Assistance publique-Hôpitaux de Paris, Hôpital Cochin

    Paris, 75014, France

Conditions

Explore the condition pages connected to this study.