Which pill prepares the cervix best? a Head-to-Head trial of mifepristone vs misoprostol

NCT ID NCT06502158

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This pilot trial tests whether mifepristone or misoprostol works better for preparing the cervix before a procedural abortion between 12 and 16 weeks of pregnancy. About 94 English- or Spanish-speaking participants will receive one of the two drugs, and doctors will measure how often each achieves the right amount of cervical dilation. The goal is to see if one approach leads to fewer complications and smoother procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mifepristone or misoprostol
What this could lead to
If one drug works better, it could simplify cervical preparation before abortion procedures, making them safer and more efficient.
What could go wrong
This is a small pilot study, so results may not apply broadly. Both drugs have known side effects like cramping and nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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