New filler gel aims to restore youthful cheeks

NCT ID NCT05452070

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an injectable gel called HArmonyCa lidocaine for filling out the mid face area in adults. About 171 participants were split into two groups: one received the gel right away, the other waited 3 months. Researchers checked for side effects and how well the gel improved cheek volume over up to 25 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HArmonyCa lidocaine injectable gel (dermal filler)

What this could lead to

If it works, this could offer a safe and effective option for restoring mid face volume loss due to aging.

What could go wrong

This is a completed phase 3 trial, but results are not yet published. As with any filler, risks include swelling, bruising, or uneven results.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bertucci MedSpa Inc. /ID# 246496

    Woodbridge, Ontario, L4L 8E2, Canada

  • Dermetics Cosmetic Dermatology /ID# 246536

    Burlington, Ontario, L7N 3N2, Canada

  • Dr Nestor's Medical Cosmetic Centre /ID# 246406

    Edinburgh, EH3 6RS, United Kingdom

  • Erevna Innovations Inc. /ID# 240401

    Westmount, Quebec, H3C 1Z3, Canada

  • Humphrey & Beleznay Cosmetic Dermatology /ID# 239805

    Vancouver, British Columbia, V5Z 4E1, Canada

  • Instituto Medico Miramar /ID# 240939

    Málaga, Malaga, 29016, Spain

  • MediZen /ID# 240102

    Sutton Coldfield, B74 2UG, United Kingdom

  • Pacific Derm /ID# 240785

    Vancouver, British Columbia, V6H 4E1, Canada

  • Skin Matters Medical Aesthetic Centre /ID# 239986

    Vancouver, British Columbia, V6M 4J2, Canada

  • The Centre for Clinical Trials /ID# 246409

    Oakville, Ontario, L6J 7W5, Canada

  • WM Hospitals /ID# 245747

    Barcelona, 08006, Spain

  • YVR Aesthetics Training & Study Centre /ID# 239809

    Vancouver, British Columbia, V5Z 1H2, Canada