Saliva test could personalize care for Opioid-Affected newborns
NCT ID NCT05937594
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at tiny molecules called microRNAs in the saliva of newborns exposed to opioids before birth. Researchers want to see if these molecules can predict how severe withdrawal symptoms will be and guide treatment. The goal is to move away from one-size-fits-all care and toward personalized medicine for babies with neonatal abstinence syndrome. Fifty infants will be enrolled to measure microRNA levels and track their development.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a simple saliva test to help doctors tailor treatment for each baby with opioid withdrawal, potentially reducing hospital stays and improving development.
What could go wrong
This is a small, early-stage study focused on finding biomarkers, not testing a treatment. The results may not lead to immediate changes in care or apply to all babies.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NEONATAL ABSTINENCE SYNDROME are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Penn State Milton S. Hershey Medical Center
RECRUITINGHershey, Pennsylvania, 17033, United States