Silver-and-Gallium dressing aims to heal skin graft wounds faster

NCT ID NCT07695688

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This trial tests a new wound dressing called Microlyte DualGuard on people who need a skin graft. The dressing contains tiny amounts of silver and gallium to prevent infection and keep the wound moist. Researchers want to see if it helps the donor site heal faster, with less pain, itching, and scarring. The study follows participants for 12 weeks after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Microlyte DualGuard wound dressing (a synthetic absorbent sheet with ionic silver and gallium)
What this could lead to
If effective, this dressing could speed up healing of skin graft donor sites, reduce infection, pain, and scarring, and improve patient comfort.
What could go wrong
This is a small feasibility study, so results may not apply to all patients. The dressing might not improve healing over standard care, and rare allergic reactions or infections are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 53 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

22 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patients where creation of a donor site wound for any indication including chronic wound, burn wound, surgical/traumatic wound, and tumor excision is indicated. 2. Thigh donor site wound (DSW) location. 3. At least 22 years of age. 4. Ability to understand and provide a signed and dated informed consent form. 5. Stated willingness to comply with all study procedures and availability for all visits for the duration of the study. 6. All female subjects of childbearing potential (not surgically sterile or postmenopausal) and male subjects with female partners of childbearing potential must agree to use effective contraception (such as implants, injectables, combined oral contraceptives, intrauterine device, sexual abstinence, vasectomy or vasectomized partner) for the duration of the study (84 days). 7. Fitzpatrick Skin Type (FST I-VI) assessment and documentation at baseline. Subjects of all FST categories (I-VI) are eligible, and the enrollment strategy will ensure that the full range of FST is represented in the study population (10% minimum enrollment in each FST sub-category). Exclusion Criteria: 1. DSW size of \> 310 cm2 2. Calculated glomerular filtration rate (GFR) \<60 ml/min 3. Hypocalcemia defined as serum corrected calcium of \<8.0 mg/dl 4. Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \> 1.5 times the upper limit of normal (ULN). 5. Serum Creatinine \> 2.0 mg/dL. 6. Pregnant, lactating or nursing women. 7. Unable to provide consent. 8. Prior adverse reaction or known sensitivity to silver or gallium. 9. Enrollment in another interventional trial using a systemic therapeutic within 30 days prior to enrollment for this study. 10. Presumed impairment of wound healing as with prescription drugs or medical diagnoses that have potential to impair wound healing at the discretion of clinical investigator, e.g., cancer, transplant status, autoimmune disease, severe malnutrition, etc. 11. Any diagnosis with concern for 30-Day mortality. 12. Any condition that might impair the evaluation of subject safety or that in the investigator opinion would interfere with study requirements.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Medstar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • University Medical Center New Orleans, LSU Health NOLA

    New Orleans, Louisiana, 70112, United States

  • Valleywise Health Medical Center

    Phoenix, Arizona, 85008, United States

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