Silver-and-Gallium dressing aims to heal skin graft wounds faster
NCT ID NCT07695688
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This trial tests a new wound dressing called Microlyte DualGuard on people who need a skin graft. The dressing contains tiny amounts of silver and gallium to prevent infection and keep the wound moist. Researchers want to see if it helps the donor site heal faster, with less pain, itching, and scarring. The study follows participants for 12 weeks after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Microlyte DualGuard wound dressing (a synthetic absorbent sheet with ionic silver and gallium)
- What this could lead to
- If effective, this dressing could speed up healing of skin graft donor sites, reduce infection, pain, and scarring, and improve patient comfort.
- What could go wrong
- This is a small feasibility study, so results may not apply to all patients. The dressing might not improve healing over standard care, and rare allergic reactions or infections are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 53 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Aug 2026
An estimate. Start dates often move.
- Expected to finish
-
Aug 2027
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
22 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adult patients where creation of a donor site wound for any indication including chronic wound, burn wound, surgical/traumatic wound, and tumor excision is indicated. 2. Thigh donor site wound (DSW) location. 3. At least 22 years of age. 4. Ability to understand and provide a signed and dated informed consent form. 5. Stated willingness to comply with all study procedures and availability for all visits for the duration of the study. 6. All female subjects of childbearing potential (not surgically sterile or postmenopausal) and male subjects with female partners of childbearing potential must agree to use effective contraception (such as implants, injectables, combined oral contraceptives, intrauterine device, sexual abstinence, vasectomy or vasectomized partner) for the duration of the study (84 days). 7. Fitzpatrick Skin Type (FST I-VI) assessment and documentation at baseline. Subjects of all FST categories (I-VI) are eligible, and the enrollment strategy will ensure that the full range of FST is represented in the study population (10% minimum enrollment in each FST sub-category). Exclusion Criteria: 1. DSW size of \> 310 cm2 2. Calculated glomerular filtration rate (GFR) \<60 ml/min 3. Hypocalcemia defined as serum corrected calcium of \<8.0 mg/dl 4. Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \> 1.5 times the upper limit of normal (ULN). 5. Serum Creatinine \> 2.0 mg/dL. 6. Pregnant, lactating or nursing women. 7. Unable to provide consent. 8. Prior adverse reaction or known sensitivity to silver or gallium. 9. Enrollment in another interventional trial using a systemic therapeutic within 30 days prior to enrollment for this study. 10. Presumed impairment of wound healing as with prescription drugs or medical diagnoses that have potential to impair wound healing at the discretion of clinical investigator, e.g., cancer, transplant status, autoimmune disease, severe malnutrition, etc. 11. Any diagnosis with concern for 30-Day mortality. 12. Any condition that might impair the evaluation of subject safety or that in the investigator opinion would interfere with study requirements.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Wound care are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
3 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Medstar Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
-
University Medical Center New Orleans, LSU Health NOLA
New Orleans, Louisiana, 70112, United States
-
Valleywise Health Medical Center
Phoenix, Arizona, 85008, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Light therapy may soothe cesarean wounds and cut painkiller use
- Can healing at home beat hospital care for bedsores?
- MuseCells under the microscope: 5-Year registry tracks Real-World outcomes
- AI-Powered smartphone photos could revolutionize wound care
- No stitches needed: new skin glue closes wounds faster
- Digital coach for nurses aims to end guesswork in wound care