Could brain immune activity predict MS lesion growth?
NCT ID NCT04625049
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 36 times
Summary
This study follows 100 people with multiple sclerosis over 10 years to see if increased activity of certain brain immune cells (microglia) around lesion edges is linked to faster lesion growth. Participants will have PET and MRI scans at the start and again during follow-up. The goal is to better understand how these immune cells might drive disease progression.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MULTIPLE SCLEROSIS are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Turku PET Centre
Turku, Southwest Finland, 20520, Finland
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help identify which MS patients are at higher risk for faster lesion growth, guiding more personalized monitoring or treatment.
What could go wrong
This is an observational study, not a treatment trial. It only looks at links between brain activity and lesion changes, so it cannot prove cause and effect or lead directly to a new therapy.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.