New hope for rare fat disorder: drug switch trial underway

NCT ID NCT06548100

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 29 times

Summary

This study tests a new experimental drug, mibavademab, in people with generalized lipodystrophy (GLD), a rare condition where the body can't store fat properly. Participants currently on the standard treatment metreleptin will switch to mibavademab to see if it is safe and tolerable. The study involves 9 adults and focuses on side effects and how the drug works in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health

    Bethesda, Maryland, 20892, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.