Could a simple breathing device slow ALS cough decline?

NCT ID NCT06119087

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 37 times

Summary

This study tests if using a mechanical insufflation device (BiWaze Cough) twice daily for 6 months can slow the loss of cough strength in people with early ALS. Twenty adults with ALS will use the device at home with a caregiver's help. Researchers will measure changes in peak cough flow and compare them to a similar group not using the device.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

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