Can a heart drug make surgery safer? new trial investigates

NCT ID NCT07597564

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether combining two drugs, metoprolol and sufentanil, can prevent sudden spikes in heart rate and blood pressure when a breathing tube is placed during general anesthesia. 900 adults having non-cardiac surgery will receive different dose combinations. The goal is to find the best balance for a smoother, safer intubation.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
metoprolol and sufentanil
What this could lead to
If successful, this could lead to a safer, more stable way to manage heart rate and blood pressure during breathing tube insertion for surgery.
What could go wrong
This is a phase 4 trial focused on short-term stability during a routine procedure, not a cure or major breakthrough. Results may not apply to patients with heart or lung conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fujian provincial hospital

    Fuzhou, Fujian, 350000, China

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