New combo therapy shows promise for vitiligo

NCT ID NCT04237103

First seen Feb 01, 2026 · Last updated May 16, 2026 · Updated 15 times

Summary

This study tested whether adding methotrexate (a medication) to UVB light therapy helps adults with active, widespread vitiligo regain skin color. 32 participants were randomly assigned to receive either the combination or light therapy alone. The main goal was to measure changes in vitiligo severity using the VASI score. Results help determine if the combination is more effective and safe than light therapy alone.

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Contacts and locations

Locations

  • Centre Hospitalier de Pau

    Pau, 64000, France

  • Centre Hospitalier de Périgueux

    Périgueux, 24000, France

  • Service de Dermatologie - CHU de Toulouse - Hopital Purpan

    Toulouse, 31059 Toulouse Cedex, France

  • Service de Dermatologie - Hôpital Saint-André

    Bordeaux, Bordeaux, 33075, France

Conditions

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